Phenotype

Disease model

Age (weeks)

Number of measures

Coat colour

7

4

Ear punch

Wound healing

7 and 17

1

Novel cage activity

Anxiety

8

2

Zero maze

Anxiety

9

4

Shuttle box

Anxiety

10

4

Glucose tolerance

Type II diabetes

11

6

Cardiovascular function

Hypertension

12

2

Body weight

Obesity

13

1

Basal hematology

13

26

Basal immunology

13

34

Experimental autoimmune encephalomyelitis

Multiple sclerosis

13 - 17

11

Serum biochemistry

17

15

Arterial elastic lamina ruptures

17

6

Renal agenesis

17

1

Bone mass and strength

Osteoporosis

17

43